Bruise-like cutaneous lesions as the early presentation of blastic plasmacytoid dendritic cell neoplasm
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چکیده
منابع مشابه
Blastic Plasmacytoid Dendritic Cell Neoplasm; A Report of Three Cases
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematodermic myeloid malignancy that is known to be derived from plasmacytoid dendritic cells which are characterized by expression of CD4, CD56, and more specific markers such as CD123. Here, the authors present three cases of BPDCN diagnosed in the past two years and address different available diagnostic modalities such as morpho...
متن کاملA Rare Case of Acute Leukemic Presentation of Blastic Plasmacytoid Dendritic Cell Neoplasm without Cutaneous Lesions
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy with a clinically aggressive phenotype arising from CD4/CD56-expressing plasmacytoid dendritic cell precursors [1]. BPDCN was categorized under “AML and related precursor neoplasms” by the 2008 WHO classification, with most cases having been previously classified as blastic natural killer (NK)-cell lymphoma/...
متن کاملBlastic Plasmacytoid Dendritic Cell Neoplasm
Introduction Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, highly aggressive hematopoietic malignancy. It manifests as cutaneous and bone marrow involvement and leukemic spread. It represents 0.7% of primary cutaneous lymphomas. Recently, it was established as a distinct entity. We present a rare case of BPDCN with good response to chemotherapy and review the clinicopathologic...
متن کاملBlastic plasmacytoid dendritic cell neoplasm.
A 81-year-old man had multiple skin lesions (brown-red plaques on the face, abdomen, and back) and asthenia. There was no hepatosplenomegaly or adenopathy. Despite normal blood count values, the peripheral smear contained blasts (7%). Bone marrow examination showed 50% of blasts and mild erythroid dysplasia. The abnormal cells were medium-sized with blastic round (panels A-B) or convoluted (pan...
متن کاملBlastic plasmacytoid dendritic cell neoplasm*
Blastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination. We report the case of a 76-year-old man with a 2 month history of violaceous nodules and a tumor with stony consistency, located on the head, and mandibular, cervical and supraclavicular lymphadenopathies. Multiple thoracic and abdominal ad...
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ژورنال
عنوان ژورنال: Dermatologica Sinica
سال: 2014
ISSN: 1027-8117
DOI: 10.1016/j.dsi.2013.07.002